Trophic action of epidermal growth factor on human duodenal mucosa cultured in vitro.

نویسندگان

  • D N Challacombe
  • E E Wheeler
چکیده

The action of epidermal growth factor on the human duodenal mucosa has been studied by estimating the crypt cell production rate in cultured explants, using a stathmokinetic technique with crypt microdissection. The addition of epidermal growth factor (400 ng/ml) to paired explants from five patients caused an almost fivefold increase in the crypt cell production rate, showing that epidermal growth factor has a trophic action on the human duodenal mucosa in vitro.

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عنوان ژورنال:
  • Gut

دوره 32 9  شماره 

صفحات  -

تاریخ انتشار 1991